Monoclonal Antibody to human C9 neoepitope (Clone: aE11)
Figure-1: Immuno Histochemical analysis of human C9 neoepitope (Clone: aE11) in Vascular endothelial and dendritic cells of germinal center of human.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Mouse IgG2a, kappa |
| Purification : | Protein G Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles |
The TCC consisting of C5b, C6, C7, C8, and C9, contains neoantigens that are absent from the individual native components. Neoantigens are present both in the MAC and the fluid-phase (SC5b-9) complex. This membrane attack complex forms channels in target cell membranes which is leading by osmotic leakag to cell lysis. The complexes contain neoantigens that are absent from the individual native components from which they are formed and DIA 011-01 is directed against a neoepitope exposed on C9 when incorporated into the TCC.
Immunohistochemical analysis: 1:5-1:10 dilution
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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