Monoclonal Antibody to Human CD4 (Clone: OKT4) PE Conjugated
Fig-1: Cell Surface flow analysis of PE conjugated hCD4 in PBMC using 0.2 µg/10^6 cells (5 µl/ test). Green represents PE conjugated isotype control (ABEOMICS); red represents PE Conjugated anti-hCD4 antibody (10-4159-P).
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| Format : | Purified |
| Amount : | 100 Test |
| Isotype : | Mouse IgG2b Kappa |
| Purification : | Protein G Chromatography |
| Content : | 25 Test in 125 µl/100 Test in 500 µl PBS containing 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. |
FACS: 0.5-1 µg/10^6 cells (5µl/10^6 cells)
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cell membrane |
| Post transnational modification: | Phosphorylated by PKC; phosphorylation at Ser-433 plays an important role for CD4 internalization. |
| Tissue Specificity: | Highly expressed in T-helper cells. The presence of CD4 is a hallmark of T-helper cells which are specialized in the activation and growth of cytotoxic T-cells, regulation of B cells, or activation of phagocytes. CD4 is also present in other immune cells such as macrophages, dendritic cells or NK cells. |
| BioGrid: | 107358. 94 interactions. |
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