Monoclonal Antibody to CD10 (Clone: CB-CALLA)
Figure-1: Cell Surface flow analysis of hCD10 in PBMC (Lymphocyte gated) using 1 µg/10^6 cells. Green represents isotype control (ABEOMICS); red represents anti-CD10 antibody (10-4131, clone:CB-CALLA). Goat anti-mouse PE conjugated secondary antibody (ABEOMICS) was used.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Mouse IgG2b Kappa |
| Purification : | Protein G Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
| Gene : | MME |
| Gene ID : | 4311 |
| Uniprot ID : | P08473 |
| Alternative Name : | Neprilysin, Atriopeptidase, Common acute lymphocytic leukemia antigen, Enkephalinase, Neutral endopeptidase 24.11, Skin fibroblast elastase, SFE |
| Immunogen Information : | Full length recombinant protein of human CD10 was used as immunogen for this antibody. |
CD10 is a membrane-associated neutral peptidase, also known as neprilysin, enkephalinase, common acute lymphoblastic leukemia antigen, and neutral endopeptidase. It acts as a cell surface enzyme with neutral metalloendopeptidase activity, is a marker for intestinal epithelial brush border. It is also present in normal bile ducts and gallbladder epithelia but is absent in cholangiocarcinomas.
FACS: 1-2 µg/10^6 cells
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cell membrane |
| Post transnational modification: | Glycosylation at Asn-628 is necessary both for surface expression and neutral endopeptidase activity. |
| BioGrid: | 110455. 102 interactions. |
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