Monoclonal Antibody to GRP94 / HSP90B1 (Endoplasmic Reticulum Marker)(Clone : SPM249)

Product code: 36-1765

Clone name : SPM249
Clonality : Monoclonal
Application : FACS, IF, WB, IHC
Reactivity : Human, Rat, Mouse, Hamster

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100 µg
$520.00 

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Format : Purified
Amount : 100 µg
Isotype : Rat IgG2a, kappa
Purification : Affinity Chromatography
Content : 100 µg in 500 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : HSP90B1
Gene ID : 7184
Uniprot ID : P14625
Alternative Name : HSP90B1, GRP94, TRA1
Immunogen Information : Purified glucose regulated protein 94 (grp94) from chicken oviducts
Recognizes a protein of 94kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96). Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90). This MAb is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grp s are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer.

Flow Cytometry (1-2ug/million cells); Immunofluorescence (1-2ug/ml); Western Blot (1-2ug/ml); Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes);

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Endoplasmic reticulum lumen, Melanosome
BioGrid: 113036. 159 interactions.
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