Monoclonal Antibody to FSH Receptor (Clone: ABM5D29)
Fig-1: Western blot analysis of FSH Receptor. Anti-FSH Receptor antibody (Clone: ABM5D29) was used at 2 µg/ml on Hela lysate.
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Format : | Purified |
Amount : | 100 µg |
Isotype : | Mouse IgG1, kappa |
Purification : | Protein G Chromatography |
Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
FSH receptor is a member of the G protein coupled receptor family consisting of 9 introns and 10 exons and a promoter region and is located on chromosome 2p21. FSH receptor was shown to be expressed selectively on the luminal surface of tumor blood vessels. A general characteristic of the blood vessels that express the endothelial FSH receptor is that they are located at the periphery of the tumors. Many studies showed that FSH receptor polymorphisms at positions 307 and 680 may be even more relevant for clinical practice for the reasons of regulating the ovarian reaction to hormone, controlling ovarian hyperstimulation, changing the menstrual cycle, and causing POF (Premature Ovarian Failure) and PCOS (Polycystic Ovary Syndrome).
WB: 2-4 µg/ml, FACS: 0.5-1 µg/10^6
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
Subcellular location: | Cell membrane |
Post transnational modification: | N-glycosylated; indirectly required for FSH-binding, possibly via a conformational change that allows high affinity binding of hormone. |
Tissue Specificity: | Sertoli cells and ovarian granulosa cells. |
BioGrid: | 108770. 34 interactions. |
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