Monoclonal antibody to FOXA1 (Clone: ABM4A82)
Fig:1- Expression analysis of FOXA1. Anti-FOXA1 antibody (Clone: ABM4A82) was tested at 2 µg/ml on HEK 293 lysate.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Mouse IgG2b Kappa |
| Purification : | Protein G Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
FoxA1 (forkhead box A1), also called HNF-3 alpha (hepatocyte nuclear factor 3 alpha) or TCF3A (transcription factor 3A) is a 473 amino acid (aa), 49 kDa (predicted) protein of the forkhead nuclear transcription factor family. Also known as hepatocyte nuclear factors, which are transcriptional activators for liver-specific transcripts such as albumin and transthyretin. The HNF3 family, including HNF3A, HNF3B, and HNF3G, are members of the forkhead class of DNA-binding proteins. It regulates transcription downstream of the estrogen receptor and other steroid hormone receptors.
Western blot analysis: 2-4 µg/ml; Immunohistochemestry: 5-10 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Nucleus |
| Tissue Specificity: | Highly expressed in prostate and ESR1-positive breast tumors. Overexpressed in esophageal and lung adenocarcinomas. |
| BioGrid: | 109411. 287 interactions. |
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