Monoclonal antibody to FLT3/CD135 (Clone: ABM5C12)
Fig:1- Expression analysis of FLT3. Anti-FLT3 antibody (Clone: ABM5C12) was tested at 4 µg/ml on Jurkat lysate.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Mouse IgG2b, k |
| Purification : | Protein G Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
Western blot analysis: 4-6 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Membrane, Endoplasmic reticulum lumen |
| Post transnational modification: | Rapidly ubiquitinated by UBE2L6 and the E3 ubiquitin-protein ligase SIAH1 after autophosphorylation, leading to its proteasomal degradation. |
| Tissue Specificity: | Detected in bone marrow, in hematopoietic stem cells, in myeloid progenitor cells and in granulocyte/macrophage progenitor cells (at protein level). Detected in bone marrow, liver, thymus, spleen and lymph node, and at low levels in kidney and pancreas. Highly expressed in T-cell leukemia. |
| BioGrid: | 108610. 14 interactions. |
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