Monoclonal antibody to FLT3/CD135 (Clone: ABM5C12)

Product code: 10-7584

Clone name : ABM5C12
Clonality : Monoclonal
Application : WB
Reactivity : Human

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Available Pack Size(s)

  •   25 µg

  •  100 µg

  • $110.00 

  • $290.00 

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Shipping Info:

Order now and get it on Wednesday December 25, 2024

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Format : Purified
Amount : 100 µg
Isotype : Mouse IgG2b, k
Purification : Protein G Chromatography
Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : FLT3
Gene ID : 2322
Uniprot ID : P36888
Alternative Name : FLT3, CD135, FLK2, STK1
Immunogen Information : A partial length recombinant protein from C terminal portion of Flt3/CD135 was used as the immunogen for this antibody.

Western blot analysis: 4-6 µg/ml

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Membrane, Endoplasmic reticulum lumen
Post transnational modification: Rapidly ubiquitinated by UBE2L6 and the E3 ubiquitin-protein ligase SIAH1 after autophosphorylation, leading to its proteasomal degradation.
Tissue Specificity: Detected in bone marrow, in hematopoietic stem cells, in myeloid progenitor cells and in granulocyte/macrophage progenitor cells (at protein level). Detected in bone marrow, liver, thymus, spleen and lymph node, and at low levels in kidney and pancreas. Highly expressed in T-cell leukemia.
BioGrid: 108610. 14 interactions.
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