Monoclonal antibody to EpCAM (Clone: ABM4D85 )

Product code: 10-7578

Clone name : ABM4D85
Clonality : Monoclonal
Application : FACS, WB
Reactivity : Human

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Price

Available Pack Size(s)

  •   25 µg

  •  100 µg

  • $110.00 

  • $290.00 

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Shipping Info:

Order now and get it on Wednesday November 27, 2024

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Format : Purified
Amount : 100 µg
Isotype : Mouse IgG2a Kappa
Purification : Protein G Chromatography
Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : EPCAM
Gene ID : 4072
Uniprot ID : P16422
Alternative Name : EPCAM, GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1
Immunogen Information : A partial length recombinant human EpCAM protein (amino acids 11-236 ) was used as the immunogen for this antibody.

EpCAM is a Mr 40,000, type I transmembrane glycoprotein that consists of two epidermal growth factor-like extracellular domains, a cysteine-poor region, a transmembrane domain, and a short cytoplasmic tail. EpCAM is encoded by the GA733-2 gene located on the long arm of chromosome 4. EpCAM has been described by various names, including those associated with monoclonal antibodies specific for the cell surface antigen (MH99, AUA1, MOC31, 323/A3, KS1/4, GA733, and HEA125) and cDNA clones used to define the antigen KS 1/4, EGP, EGP40, and GA733-2.

Western blot analysis: 0.01-0.02 µg/ml, Flowcytometric analysis: 0.5-1 µg/10^6 cells

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Lateral cell membrane, Cell junction
Post transnational modification: Hyperglycosylated in carcinoma tissue as compared with autologous normal epithelia. Glycosylation at Asn-198 is crucial for protein stability.
BioGrid: 110250. 5 interactions.
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