Monoclonal Antibody to Ep-CAM / CD326 (Epithelial Marker)(Clone : SPM134)

Product code: 36-1403

Clone name : SPM134
Clonality : Monoclonal
Application : IF, IHC
Reactivity : Human

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100 µg
$520.00 

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Format : Purified
Amount : 100 µg
Isotype : Mouse IgG1, kappa
Purification : Affinity Chromatography
Content : 100 µg in 500 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : EPCAM
Gene ID : 4072
Uniprot ID : P16422
Alternative Name : EPCAM, GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1
Immunogen Information : Small cell lung carcinoma cells
EGP40 is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.

Immunofluorescence (1-2ug/ml); Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 min at RT),(Staining of formalin/paraffin tissues REQUIRES digestion of tissue sections with pepsin at 1mg/ml Tris-HCl, pH 2.0 for 15 min at RT or 10 min at 37C),

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Lateral cell membrane, Cell junction
Post transnational modification: Hyperglycosylated in carcinoma tissue as compared with autologous normal epithelia. Glycosylation at Asn-198 is crucial for protein stability.
BioGrid: 110250. 5 interactions.
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