Monoclonal Antibody to Mouse EBI3 (Clone: ABM2C40)

Product code: 10-4021

Clone name : ABM2C40
Clonality : Monoclonal
Application : WB
Reactivity : Mouse

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Available Pack Size(s)

  •   25 µg

  •  100 µg

  • $110.00 

  • $290.00 

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Shipping Info:

Order now and get it on Wednesday December 25, 2024

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Format : Purified
Amount : 100 µg
Isotype : Rat IgG2b Kappa
Purification : Protein G Chromatography
Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : Ebi3
Gene ID : 50498
Uniprot ID : O35228
Alternative Name : Ebi3, Il27b
Immunogen Information : A full length recombinant mEBI3 protein was used as the immunogen for this antibody.

Epstein-Barr Virus Induced Gene 3 (EBI3) is an immune regulator that has been associated with the pathogenesis of inflammatory bowel disease. EBI3, as part of the immunosuppressive IL-35 cytokine, plays an important role in the regulation of intestinal immune responses by controlling overwhelming T-cell activation. EBI3 deficiency does not lead to changes in intestinal pathology in trinitrobenzene sulfonic acid colitis, but is protective in oxazolone-induced colitis.

Western blot analysis: 2-4 µg/ml

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Secreted
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