Monoclonal Antibody to CD90 / Thy1 (Stromal / Mesenchymal Marker)(Clone : AF-9)

Product code: 36-1737

Clone name : AF-9
Clonality : Monoclonal
Application : FACS, IF
Reactivity : Human

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100 µg
$520.00 

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Format : Purified
Amount : 100 µg
Isotype : Mouse IgG1, kappa
Purification : Affinity Chromatography
Content : 100 µg in 500 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : THY1
Gene ID : 7070
Uniprot ID : P04216
Alternative Name : THY1
Immunogen Information : Human T-lymphoma cells

Recognizes a protein of 18-35kDa, identified as CD90 (also known as Thy1). CD90 is a member of the immunoglobulin superfamily. It may contribute to inhibition of proliferation/differentiation of hematopoietic stem cells and neuron memory formation in the CNS. It consists of a single Ig domain (112 amino acids; 25-35 kDa) inserted into the cell membrane via a GPI anchor. Expressed by hematopoietic stem cells and neurons in all species studied. Its highly expressed in connective tissue and various fibroblast and stromal cell lines, expressed on all thymocytes and peripheral T cells in mice, but in humans expressed only on small % fetal thymocytes, 10-40% of CD34+ cells in bone marrow, and <1% of CD3+CD4+ lymphocytes in peripheral circulation. It is also expressed by human lymph node HEV endothelium but not other endothelia. Lastly, it is expressed by a limited number of lymphoblastoid and leukemic cell lines

Flow Cytometry (1-2ug/million cells); Immunofluorescence (1-2ug/ml);

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cell membrane
BioGrid: 112926. 37 interactions.
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