Monoclonal Antibody to CD3 (Clone: OKT3) APC Conjugated
Fig-1: Cell surface flow analysis of hCD3 in PBMC using 0.5 µg/10^6 cells. Green represents isotype control (ABEOMICS); red represents APC conjugated anti-hCD3 antibody (10-4089AC).
Roll over image to zoom in
Shipping Info:
Order now and get it on Wednesday December 25, 2024
Same day delivery FREE on San Diego area orders placed by 1.00 PM
Format : | Purified |
Amount : | 100 Test |
Isotype : | Mouse IgG2a Kappa |
Purification : | Protein G Chromatography |
Content : | 0.04 mg/ml in PBS with 0.05% Azide. |
Storage condition : | Store the antibody at 4°C, stable for 6 months. |
CD3D is one of the several invariant chains that the variable chains of TCR: Alpha beta or Gamma delta TCR contains, and which support surface TCR expression and transduce the TCR signal. CD3D, along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK).
FACS analysis: 0.1- 0.5 µg/10^6 cells
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
Subcellular location: | Cell membrane |
Post transnational modification: | Phosphorylated on Tyr residues after T-cell receptor triggering by LCK in association with CD4/CD8. |
Tissue Specificity: | CD3D is mostly present on T-lymphocytes with its TCR-CD3 partners. Present also in fetal NK-cells. |
BioGrid: | 107353. 9 interactions. |
There are currently no product reviews
|