Monoclonal Antibody to CD26 (DPP IV / ADA-Binding Protein)(Clone : DPP4/910)

Product code: 36-1085

Clone name : DPP4/910
Clonality : Monoclonal
Application : FACS, IF, IHC
Reactivity : Rat, Human

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100 µg
$520.00 

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Shipping Info:

For estimated delivery dates, please contact us at [email protected]


Format : Purified
Amount : 100 µg
Isotype : Mouse IgG2b, kappa
Purification : Affinity Chromatography
Content : 100 µg in 500 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : DPP4
Gene ID : 1803
Uniprot ID : P27487
Alternative Name : DPP4, ADCP2, CD26
Immunogen Information : Recombinant human DPP4 protein

Recognizes a glycoprotein of 110kDa, identified as CD26. It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection.

Flow Cytometry (1-2ug/million cells); Immunofluorescence (1-2ug/ml); Immunohistochemistry (Frozen Only) (1-2ug/ml for 30 minutes at RT)

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cell membrane, Apical cell membrane, Cell projection, Cell projection, Cell junction, Membrane raft
Post transnational modification: Phosphorylated. Mannose 6-phosphate residues in the carbohydrate moiety are necessary for interaction with IGF2R in activated T-cells. Mannose 6-phosphorylation is induced during T-cell activation.
Tissue Specificity: Expressed specifically in lymphatic vessels but not in blood vessels in the skin, small intestine, esophagus, ovary, breast and prostate glands. Not detected in lymphatic vessels in the lung, kidney, uterus, liver and stomach (at protein level). Expressed in the poorly differentiated crypt cells of the small intestine as well as in the mature villous cells. Expressed at very low levels in the colon.
BioGrid: 108137. 8 interactions.
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