Monoclonal antibody to CD247/CD3 Zeta (TCRζ, CD3ζ) (Clone: 6B10.2)
Figure-1: Western blot analysis of CD247. Anti-CD247 antibody (Clone: 6B10.2) was used at 1 µg/ml on (1) Jurkat, (2) Daudi and (3) Raw lysates. Jurkat showing high expression and Daudi, Raw showing no expressions.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Mouse IgG1 Kappa |
| Purification : | Affinity chromatography |
| Content : | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Storage condition : | The antibody solution should be stored undiluted between 2°C and 8°C. |
The invariant TCR zeta chain is a member of the CD3 complex associated with the clonotypic alpha/beta TCR heterodimer. The disulfide-linked TCR zeta homodimers transmit signals following TCR ligation. Loss of TCR zeta expression has been reported in a diverse range of disease states, including autoimmune diseases, many neoplastic conditions and chronic infections, such as tuberculosis and leprosy.
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