Monoclonal antibody to CD244/p38 (Clone: C1.7)

Product code: 10-4204

Clone name : C1.7
Clonality : Monoclonal
Application : IP, ELISA, FACS, WB
Reactivity : Human

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Available Pack Size(s)

  •   25 µg

  •  100 µg

  • $110.00 

  • $290.00 

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Shipping Info:

Order now and get it on Wednesday November 27, 2024

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Format : Purified
Amount : 100 µg
Isotype : Mouse IgG1k
Purification : Protein G Chromatography
Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : CD244
Gene ID : 51744
Uniprot ID : Q9BZW8
Alternative Name : NK cell activation-inducing ligand (NAIL), NK cell type I receptor protein 2B4 (NKR2B4; h2B4), SLAM family member 4 (SLAMF4), Signaling lymphocytic activation molecule 4, 2B4
Immunogen Information : Cultured human NK cells was used as the immunogen for this antibody.

CD244, also known as 2B4, is a type I transmembrane protein with a molecular weight of 38 kD. CD244 is one of the members of the CD2 subsett of the immunoglobulin superfamily (igSF) molecules. It is expressed in a wide variety of immune cells, including NK cells, most CD8T cells, most γ/δ T cells, monocytes, eosinophils, and basophils. CD48 is the ligand of CD244. It has been reported that the ligation of human CD244 can cause enhanced NK cell cytotoxicity as well as cytokine production. Recent studies have indicated that human CD244 has inhibitory and activating functions, similar to that of murine CD244. These functions are dependent upon the density of 2B4 expression of the cell surface, the degree of ligation, and the level of adaptor molecule SAP expression.

  FACS, WB, ELISA, IP

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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