Monoclonal Antibody to CD15 / FUT4 (Reed-Sternberg Cell Marker)(FUT4/815 + BRA-4F1)

Product code: 36-1165

Clone name : FUT4/815 + BRA-4F1
Clonality : Monoclonal
Application : IHC
Reactivity : Human

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100 µg
$520.00 

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Format : Purified
Amount : 100 µg
Isotype : Mouse IgM, kappa
Purification : Affinity Chromatography
Content : 100 µg in 500 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : FUT4
Gene ID : 2526
Uniprot ID : P22083
Alternative Name : FUT4, ELFT, FCT3A
Immunogen Information : Purified human neutrophils (FUT4/815); Myelomonocytic leukemia cells (BRA-4F1)
CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0 for 45 min at 95°C followed by cooling at RT for 20 minutes)

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Golgi apparatus
BioGrid: 108802. 5 interactions.
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