Monoclonal Antibody to CD11c (Dendritic Cell Marker)(Clone : HC1/1)
FCM staining of human PBMC's using CD11c Monoclonal Antibody (HC1/1).
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Mouse IgG1, kappa |
| Purification : | Affinity Chromatography |
| Content : | 100 µg in 500 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
CD11c, also known as Integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a type I transmembrane protein found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst; expressed in hairy cell leukemias, acute non-lymphocytic leukemias, and some B-cell chronic lymphocytic leukemias.
Flow Cytometry (1-2ug/million cells); Immunofluorescence (1-2ug/ml); Functional Studies (Order Ab without BSA & Azide);
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Membrane |
| Tissue Specificity: | Predominantly expressed in monocytes and granulocytes. |
| BioGrid: | 109893. 1 interactions. |
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