Monoclonal Antibody to c-Fos (Clone: 2H2)
Figure-1: Immunofluorescent analysis of rat hippocampus section stained with mouse mAb to c-FOS,(34-1032), dilution 1:200, in red, and costained with rabbit pAb to FOX3/NeuN,(34-1036), dilution 1:3,000, in green. The blue is Hoechst staining of nuclear DNA. The (34-1032) antibody labels nuclei of spontaneously activated neurons, while FOX3/NeuN antibody stains nuclei and distal perikarya of most neurons.
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Shipping Info:
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| Format : | Purified |
| Amount : | 100 µl |
| Isotype : | Mouse, IgG1 |
| Content : | Antibody is supplied as an aliquot of 1 mg/ml of affinity purified antibody. |
| Storage condition : | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
WB: 1:500, IF/ICC or IHC: 1:500
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Nucleus, Endoplasmic reticulum, Cytoplasm |
| Post transnational modification: | In quiescent cells, the small amount of FOS present is phosphorylated at Tyr-10 and Tyr-30 by SRC. This Tyr-phosphorylated form is cytosolic. In growing cells, dephosphorylated by PTPN2. Dephosphorylation leads to the association with endoplasmic reticulum membranes and activation of phospholipid synthesis. |
| BioGrid: | 108636. 139 interactions. |
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