Monoclonal Antibody to Aurora A Kinase (Clone: 4A7)
Figure-1: HeLa cell cultures were stained with (34-1015) antibody (green). Strong staining in spindle poles is seen in cells at anaphase and the antibody also stains the midbodies between daughter cells. Cells were counterstained with chicken polyclonal antibody to vimentin (34-1126) in red, revealing cytoplasmic intermediate filaments. Blue is a DNA stain.
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Shipping Info:
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| Format : | Purified |
| Amount : | 100 µl |
| Isotype : | Mouse, IgG1 |
| Content : | Antibody is supplied as an aliquot of 1 mg/ml of affinity purified antibody. |
| Storage condition : | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
| Gene : | AURKC |
| Gene ID : | 6795 |
| Uniprot ID : | Q9UQB9 |
| Alternative Name : | Aurora 3, ARK-3, Aurora/IPL1-related kinase 3, Aurora/IPL1/Eg2 protein 2, Serine/threonine-protein kinase 13, Serine/threonine-protein kinase aurora-C |
| Immunogen Information : | Full length recombinant human Aurora C protein expressed in and purified from E. coli. |
WB: 1:1,000. ICC/IF or IHC: 1:1,000-1:2,000.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Nucleus, Chromosome, Chromosome, Cytoplasm |
| Tissue Specificity: | Isoform 1 and isoform 2 are expressed in testis. Elevated expression levels were seen only in a subset of cancer cell lines such as Hep-G2, Huh-7 and HeLa. Expression is maximum at M phase. |
| BioGrid: | 112671. 26 interactions. |
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