Anti-p34cdc2 Monoclonal Antibody (Clone: A17)
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Amount : | 100 μg/vial |
Isotype : | Mouse IgG2a |
Purification : | Ascites |
Content : | Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. Reconstitute : Add 1ml of PBS buffer will yield a concentration of 100ug/ml. |
Storage condition : | At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing. |
Gene : | Cdk1 |
Gene ID : | 54237 |
Uniprot ID : | P39951 |
Alternative Name : | Cyclin-dependent kinase 1; CDK1; 2.7.11.22; 2.7.11.23; Cell division control protein 2 homolog; Cell division protein kinase 1; p34 protein kinase; Cdk1; Cdc2, Cdc2a, Cdkn1 |
Immunogen Information : | C-terminal two-thirds of Xenopus p34cdc2 expressed in E.coli. |
P34(cdc2), also known as cell division cycle(CDC2), or cyclin-dependent kinase 1(CDK1). CDC2 is a catalytic subunit of a protein kinase complex, called the M-phase promoting factor, that induces entry into mitosis and is universal among eukaryotes. In HeLa cells CDC2 is the most abundant phosphotyrosine-containing protein and its phosphotyrosine content is subject to cell cycle regulation. CDC2 gene is located on chromosome 10.
Western blot : 0.5-1μg/ml; Immunohistochemistry(Paraffin-embedded Section) : 1-2μg/ml; Immunohistochemistry(Frozen Section) : 1-2μg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
Subcellular location: | Nucleus, Cytoplasm, Mitochondrion, Cytoplasm, Cytoplasm |
Post transnational modification: | Polyubiquitinated upon genotoxic stress. |
BioGrid: | 248460. 1 interactions. |
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