Anti-N-Cadherin Monoclonal Antibody (Clone: GC-4)(Discontinued)
Figure 1: Anti-N-Cadherin antibody(monoclonal) 39-1072. Western blotting: Lane 1: Rat Brain Tissue Lysate, Lane 2: Rat Brain Tissue Lysate, Lane 3: Rat Medulla Oblongata Tissue Lysate.
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| Amount : | 100 μg/vial |
| Isotype : | Mouse IgG1 |
| Purification : | Ascites |
| Content : | Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. Reconstitute : Add 1ml of PBS buffer will yield a concentration of 100ug/ml. |
| Storage condition : | At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing. |
N-cadherin(NCAD) is a member of the cadherin cell-cell adhesion receptor family that includes P-, E-, and R-cadherin and liver cell adhesion molecule(L-CAM). N-Cadherin,, also known as Cadherin-2, encodes a 907-amino acid protein that includes a 159-amino acid signal sequence. Human and mouse nucleotide sequences are 96% identical. Mouse Ncad gene consists of 16 exons dispersed over more than 200 kb of genomic DNA. Human N-cadherin gene contains 16 exons and its sequence is highly similar to both the mouse NCAD gene(including the large first and second introns) and other cadherin genes. N-cadherin is mapped to 18q11.2. Cadherin regulates dendritic spine morphogenesis.
Western blot : 2μg/ml; Immunohistochemistry(Frozen Section) : 4μg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cell membrane, Cell junction, Cell surface |
| Post transnational modification: | May be phosphorylated by OBSCN. |
| Tissue Specificity: | In testis, expressed in Sertoli and germ cells. |
| BioGrid: | 249720. 1 interactions. |
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