Anti-Mucin Gastric Monoclonal Antibody (Clone: 45M1)
Figure 1: Anti-Mucin Gastric antibody(39-1067). IHC(P): Human Gastric Cancer Tissue.
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| Amount : | 100 μg/vial |
| Isotype : | Mouse IgG1 |
| Purification : | Ascites |
| Content : | Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. Reconstitute : Add 1ml of PBS buffer will yield a concentration of 100ug/ml. |
| Storage condition : | At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing. |
| Gene : | MUC5AC |
| Gene ID : | 4586 |
| Uniprot ID : | P98088 |
| Alternative Name : | Mucin-5AC ; MUC-5AC ; Gastric mucin ; Lewis B blood group antigen ; LeB ; Major airway glycoprotein ; Mucin-5 subtype AC, tracheobronchial; Tracheobronchial mucin ; TBM ; MUC5AC ; MUC5 |
| Immunogen Information : | Mucin from human ovarian cyst fluid. |
Mucin 5AC (Muc5AC) is a protein that in humans is encoded by the MUC5AC gene. Using real-time RT-PCR, Moehle et al. (2006) found that MUC5AC was highly expressed in adult trachea and stomach. Expression was lower in adult lung and weak in fetal lung, and no expression was detected in other tissues. This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to chronic obstructive pulmonary disease. Moreover, Muc5ac is identified as a direct and critical mediator of resistance during intestinal nematode infection.
Western blot : 1-2μg/ml; Immunohistochemistry(Paraffin-embedded Section) : 2-4μg/ml; Immunocytochemistry : 1μg/ml;
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Secreted |
| Post transnational modification: | Proteolytic cleavage in the C-terminal is initiated early in the secretory pathway and does not involve a serine protease. The extent of cleavage is increased in the acidic parts of the secretory pathway. Cleavage generates a reactive group which could link the protein to a primary amide. |
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