Anti-MAP1 Monoclonal Antibody (Clone:HM-1)
Figure 1: Anti-MAP1 monoclonal antibody(39-1047). IHC(P): Rat Brain Tissue.
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Amount : | 100 μg/vial |
Isotype : | Mouse IgG1 |
Purification : | Ascites |
Content : | Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. Reconstitute : Add 1ml of PBS buffer will yield a concentration of 100ug/ml. |
Storage condition : | At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing. |
Microtubules are the ubiquitous cytoskeletal structural components that are involved in intracellular transport. They are composed of tubulin and microtubule-associated proteins(MAPs). MAP1 is one of the major neuronal MAPs as well as being the largest(350KD). MAPs include MAP1A, MAP1B, and MAP2. MAP1a is a single-copy gene spanning 10.5 kb. MAP1a coding sequence is contained in five exons. MAP1B is encoded as a polyprotein that is processed to form a complex N-terminal microtubule-binding domain.
Western blot : 0.5-2μg/ml; Immunohistochemistry(Paraffin-embedded Section) : 1-2μg/ml; Immunohistochemistry(Frozen Section) : 1-2μg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
Subcellular location: | Cytoplasm |
Post transnational modification: | LC2 is generated from MAP1A by proteolytic processing. It is free to associate with both MAP1A and MAP1B. |
Tissue Specificity: | Brain, heart and muscle. |
BioGrid: | 247217. 5 interactions. |
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