Anti-Cytokeratin Peptide 7 Monoclonal Antibody (Clone: LDS-68)
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Amount : | 100 μg/vial |
Isotype : | Mouse IgG1 |
Purification : | Ascites |
Content : | Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. Reconstitute : Add 1ml of PBS buffer will yield a concentration of 100ug/ml. |
Storage condition : | At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing. |
KRT7 is a type II keratin of simple nonkeratinizing epithelia. The deduced 489-amino acid protein has a calculated molecular mass of about 54 kD. K7 contains 4 central alpha-helical segments with heptad repeats of hydrophobic residues characteristic of a coiled-coil region. Within this domain, K7 shares 73% homology with epidermal K6B. KRT7 gene contains 9 exons and spans more than 15.6 kb. K7 gene is mapped to chromosome 12. Keratin 7 is expressed in a wide range of epithelial structures in humans.
Western blot : 1-2μg/ml; Immunohistochemistry(Paraffin-embedded Section) : 2-4μg/ml; Immunohistochemistry(Frozen Section) : 2-4μg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
Post transnational modification: | Arg-15 is dimethylated, probably to asymmetric dimethylarginine. |
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