Anti-Collagen, Type IV Monoclonal Antibody (Clone: COL-94)
Figure 1: Anti-Collagen, Type IV monoclonal antibody(39-1027). IHC(P): Human Mammary Cancer Tissue.
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| Amount : | 100 μg/vial |
| Isotype : | Mouse IgG1 |
| Purification : | Ascites |
| Content : | Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. Reconstitute : Add 1ml of PBS buffer will yield a concentration of 100ug/ml. |
| Storage condition : | At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing. |
Collagen IV is comprised of a third chain(alpha-3) together with the 2 classical ones, alpha-1 and alpha-2. COL4A3 gene is localized to 2q36-q37 by analysis of somatic cell hybrids and by in situ hybridization. The alpha-3 chain of type IV collagen induces autoimmune Goodpasture syndrome. Mutations in the COL4A4 and COL4A3 genes cause familial benign hematuria.
Immunohistochemistry(Paraffin-embedded Section) : 0.5-1μg/ml; Immunohistochemistry(Frozen Section) : 0.5-1μg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Secreted |
| Post transnational modification: | Proteolytic processing produces the C-terminal NC1 peptide, arresten. |
| Tissue Specificity: | Highly expressed in placenta. |
| BioGrid: | 107679. 24 interactions. |
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