Monoclonal Antibody to a-internexin/NF66 (Clone: 2E3)
Figure-1: Immunohistochemistry of a section of rat facial nucleus 7 days following axotomy. These neurons are capable of regenerating their axons and also, concomitant with regeneration, strongly upregulate α-internexin in their perikarya. Other central neurons which are not able to regenerate their axons do not upregulate this protein after axotomy and untreated facial neurons normally show only very low levels of α-internexin. Both findings suggest that α-internexin has a role in axonal regeneration.
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| Format : | T.C. Sup. |
| Amount : | 500 µl |
| Isotype : | Mouse, IgG1 |
| Content : | Antibody is supplied as an aliquot of 1 mg/ml of affinity purified antibody or tissue culture supernatant. |
| Storage condition : | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
WB: 1:10,000. IF/ICC and IHC: 1:5,000.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Post transnational modification: | O-glycosylated. |
| Tissue Specificity: | Found predominantly in adult CNS. |
| BioGrid: | 114566. 41 interactions. |
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