MMAB Recombinant Protein
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Amount : | 25 µg |
Purification : | Greater than 95.0% as determined by SDS-PAGE. |
Content : | MMAB 1mg/ml protein solution contains 20mM Tris pH-7.5 & 10% glycerol. |
Storage condition : | MMAB Human although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles. |
AA sequence : | MGSSHHHHHH SSGLVPRGSH MQSRGPQGVE DGDRPQPSSK TPRIPKIYTK TGDKGFSSTF TGERRPKDDQ VFEAVGTTDE LSSAIGFALE LVTEKGHTFA EELQKIQCTL QDVGSALATP CSSAREAHLK YTTFKAGPIL ELEQWIDKYT SQLPPLTAFI LPSGGKISSA LHFCRAVCRR AERRVVPLVQ MGETDANVAK FLNRLSDYLF TLARYAAMKE GNQEKIYKKN DPSAESEGL. |
Alternative Name : | CBIB, Cob(I)alamin adenosyltransferase, EC 2.5.1.17. |
Source : Escherichia Coli.
MMAB Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 239 amino acids (33-250 a.a.) and having a molecular mass of 26.3 kDa. The MMAB is fused to 21 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
MMAB protein catalyzes the last step in the conversion of vitamin B(12) into adenosylcobalamin (AdoCbl), a vitamin B12 containing coenzyme for methylmalonyl-CoA mutase(MCM). Decreased MMAB activity leads to the inherited disorder vitamin B12 dependent methylmalonic aciduria linked to the cblB complementation group.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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