Legionella pneumophila LPS (serogroup 1) mouse mAb
Fig-1: AWB4CE4 antibody shows specific binding to LPS antigen from Legionella pneumophila (serogroup 1).
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Format : | Purified |
Amount : | 100 µg |
Isotype : | Mouse IgG1k |
Content : | 1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% BSA |
Storage condition : | Store at -20°C. Avoid repeated freeze and thaw cycles. |
Immunogen Information : | LPS conjugated to BSA |
Legionella pneumonia, first discovered after an outbreak in Pennsylvania in 1976 at the American Legion convention, is a common cause of community-acquired pneumonia. Legionella are gram-negative bacteria found in natural aquatic environments, where they are intracellular parasites of protozoa. The serogroup 1 strains most commonly cause human infections. Serotyping can be performed by antibody subgrouping, pulsed-field gele electrophoresis, or DNA sequencing. The lipopolysaccharide, LPS or endotoxin, of serogroup 1 is a bacterial virulence factor that contains 10-75 residues of the unique sugar termed legionaminic acid. Lacking free hydroxyl groups renders this LPS hydrophobic, allowing the bacterium to adhere to target cell membranes including macrophages in the lung.
1µg/mL - 0.001µg/mL. It is recommended that the reagent be titrated for optimal performance for each application. See product image legends for additional information.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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