ING1 Recombinant Protein
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| Amount : | 20 µg |
| Purification : | Greater than 90.0% as determined by SDS-PAGE. |
| Content : | ING1 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0) and 10% glycerol. |
| Storage condition : | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| AA sequence : | MGSSHHHHHH SSGLVPRGSH MGSMLSPANG EQLHLVNYVE DYLDSIESLP FDLQRNVSLM REIDAKYQEI LKELDECYER FSRETDGAQK RRMLHCVQRA LIRSQELGDE KIQIVSQMVE LVENRTRQVD SHVELFEAQQ ELGDTAGNSG KAGADRPKGE AAAQADKPNS KRSRRQRNNE NRENASSNHD HDDGASGTPK EKKAKTSKKK KRSKAKAERE ASPADLPIDP NEPTYCLCNQ VSYGEMIGCD NDECPIEWFH FSCVGLNHKP KGKWYCPKCR GENEKTMDKA LEKSKKERAY NR. |
| Alternative Name : | Inhibitor Of Growth Family, Member 1, Growth Inhibitory Protein ING1, Tumor Suppressor ING1, Growth Inhibitor ING1, Inhibitor Of Growth Protein 1, Inhibitor Of Growth 1, P24ING1c,P33ING1b, P47ING1a, P33ING1, P33, P47, ING1 . |
Source : Escherichia Coli.
ING1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 302 amino acids (1-279 a.a) and having a molecular mass of 34.3kDa.ING1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Inhibitor of Growth Family Member 1, also known as ING1 is a tumor
suppressor protein which is able to induce cell growth arrest and apoptosis. ING1
is a nuclear protein which physically act together with the tumor suppressor
protein TP53 and is a component of the p53 signaling pathway. In addition, Reduced
expression and rearrangement of ING1 have been identified in various cancers.
Multiple alternatively spliced transcript variants encoding distinct isoforms
have been described for ING1.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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