IL-8 Leeporter™ Luciferase Reporter-RAW264.7 Cell Line
Fig-1: Induction of IL-8 promoter activity by LPS in IL-8 Leeporter™ - RAW264.7 cells.
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Shipping Info:
Order now and get it on Wednesday November 06, 2024
Same day delivery FREE on San Diego area orders placed by 1.00 PM
Amount : | 1 vial |
Content : | Each vial contains 2 ~ 3 x 10^6 cells in 1 ml of 90% FBS + 10% DMSO. |
Storage condition : | Immediately upon receipt, store in liquid nitrogen. |
The IL-8 Leeporter™ Luciferase Reporter cell line is a stably transfected RAW 264.7 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the IL-8 promoter. IL-8 is one of the key proinflammatory chemokines or cytokines, which is produced by macrophages and other epithelial cells. Induction of IL-8 is associated with inflammation. The IL-8 induction by Toll-like receptor 4 (TLR4) ligand, LPS, is shown in Figure 1.
Application:
- Monitor the IL-8 induction activity.
- Screen for activators or inhibitors of the IL-8 induction.
Culture conditions:
Functional validation:
A. Response of IL-8 Leeporter™ – RAW264.7 cells to lipopolysaccharide (LPS)
LIMITED USE RESTRICTIONS:
THIS PRODUCT IS SOLELY FOR IN VITRO RESEARCH USE ONLY. NOT FOR DIAGNOSTIC OR THERAPEUTIC USE.
By use of this product, user agrees to be bound by the terms of this limited use statement.
This product is solely for Internal Research Purposes and not for Commercial Purposes. Commercial Purposes include, but are not limited to (1) use of the cell line in manufacturing; (2) use of the cell line to provide a service, information or data; (3) use of the cell line for therapeutic, diagnostic or prophylactic purposes; or (4) resale of the cell line whether or not such cell lines are resold for use in research. The buyer cannot sell, give or otherwise transfer this product to a third party.
Commercial License Agreement is available for non-research use if applicable. Please contact Abeomics ([email protected]).
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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