IL-2 (human) (Recombinant) (untagged)

Product code: 32-190043

Application : Functional Assay
Reactivity : Human

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Available Pack Size(s)

  •  2 (human) (Recombinant) (untagged)(Discontinued)

  •  10 µg

  • $503.00 

  • $340.00 

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Amount : 10 µg
Purification : >=95% (SDS-PAGE)
Content : Reconstitute 10µg vial with 100 µl sterile water to a concentration of 0.1mg/ml.
Reconstitute 50µg vial with 100 µl sterile water to a concentration of 0.5mg/ml.
Further dilute in other aqueous solutions.
Lyophilized from sterile 0.1% TFA, 70% acetonitrile.
Storage condition : Short Term Storage +4°C ; Long Term Storage-20°C ;Avoid freeze/thaw cycles. Stable for at least 1 year after receipt when stored at -80°C.
Working aliquots are stable for up to 3 months when stored at -20°C.
AA sequence : The extracellular domain of human IL-2 (aa 21-153) with a N-terminal Met.
Alternative Name : Interleukin-2; Aldesleukin

Source :E. coli
Specific Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells, and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils, and induces mononuclear cells to secrete IFN-gamma and TNF-alpha and -beta. Moreover, studies have shown that IL-2 is required for activation-induced apoptosis, an important hemeostatic mechanism in the immune system, which is involved in the maintenance of peripheral tolerance to self-antigens.

MW :~14kDa (SDS-PAGE)
Biological Activity: Measured in a cell proliferation assay using CTLL2 cells. The ED50 for this effect is typically 0.35-1.4ng/ml.
Endotoxin Content: <0.01EU/µg protein (LAL test; Lonza).

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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