IFN a 2b 20kd-PEG Recombinant Protein
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Amount : | 10 µg |
Purification : | Greater than 97.0% as determined by SEC-HPLC. |
Content : | IFN-a 2b is supplied in solution (1.48mg/ml) containing 20mM Acetate Buffer (pH 6.0), 0.8%NaCl and 0.005% Polysorbate 80. |
Storage condition : | IFN alpha-2b PEG should be stored refrigerated at 2° to 8°C. Vials should be kept in their packaging to protect from light until the time of use. Shaking and freezing should be avoided. |
Alternative Name : | Interferon alpha 2b, IFNA, INFA2, MGC125764, MGC125765. |
Source : Escherichia Coli.
Interferon-a 2b Human Recombinant produced in E.coli is a single, non-glycosylated, polypeptide chain containing 165 amino acids and having a molecular mass of 19269 Dalton. The Pegylated IFN-a 2b is produced by attaching a 20kDa mPEG-aldehyde to the N-terminal IFN alpha-2b. Interferon-a 2b is purified by proprietary chromatographic techniques.
IFN-alpha is produced by macrophages and has antiviral activities. Interferon stimulates the production of two enzymes: protein kinase and an oligoadenylate synthetase.
The specific activity as determined in a viral resistance assay using VSV-WISH cells was found to be 3,000,000 IU/mg.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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