Human PRAME Protein, Flag Tag
Figure 1. Human PRAME Protein, Flag Tag on SDS-PAGE under reducing condition.
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| Amount : | 10µg |
| Purification : | The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| Content : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage condition : | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Gene : | PRAME |
| Uniprot ID : | P78395 |
| Alternative Name : | MAPE; OIP4; CT130; OIP-4,Recombinant human PRAME Protein with C-terminal 3?Flag tag |
This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Molecular Weight : The protein has a predicted molecular mass of 60.8 kDa after removal of the signal peptide.
Tag :C-3?Flag Tag
Molecular Weight : The protein has a predicted molecular mass of 60.8 kDa after removal of the signal peptide.
Tag :C-3?Flag Tag
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