Human LOX-1 Protein, hFc Tag

Product code: 32-18292

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  •   50 µg

  •  100 µg

  • $473.00 

  • $573.00 

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Amount : 100 µg
Purification : The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Content : Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.
Storage condition : Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Uniprot ID : P78380
Alternative Name : CLEC8A;LOX1;LOXIN;SCARE1;SLOX1;OLR1
Description :Recombinant Human LOX-1 Protein with N-terminal human Fc tag
Background: This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
Description: Recombinant Human LOX-1 Protein with N-terminal human Fc tag
Molecular Characterization: hFc(Glu99-Ala330) LOX-1(Met58-Gln273)
Molecular Weight :The protein has a predicted molecular mass of 50.9 kDa after removal of the signal peptide. The apparent molecular mass of hFc-LOX-1 is approximately 55-70 kDa due to glycosylation.
Tag :N-Human Fc Tag
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