Human Interleukin-32 alpha
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| Amount : | 100 µg |
| Purification : | Reducing and Non-Reducing SDS PAGE at >= 95% |
| Content : | Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 50 mM sodium phosphate, pH 7.5 Sterile water at 0.1 mg/mL |
| Storage condition : | Store at -20°C |
| AA sequence : | MCFPKVLSDD MKKLKARMHQ AIERFYDKMQ NAESGRGQVM SSLAELEDDF KEGYLETVAA YYEEQHPELT PLLEKERDGL RCRGNRSPVP DVEDPATEEP GESFCDKSYG APRGDKEELT PQKCSEPQSS K |
Source: Genetically modified E.coli.
Predicted MW:Â Monomer, 14.9 kDa (131 aa)
Interleukin 32 alpha (IL-32 alpha) is one of six known splice variants of the IL-32 gene. IL-32 alpha induces the macrophage production of inflammatory cytokines, such as interleukin 8 (IL-8), tumor necrosis factor-alpha (TNF-alpha), and macrophage inflammatory protein 2 (MIP-2). IL-32 alpha expression is increased after the activation of T cells, natural killer (NK) cells, and interferon gamma-treated epithelial cells.
Predicted MW:Â Monomer, 14.9 kDa (131 aa)
Interleukin 32 alpha (IL-32 alpha) is one of six known splice variants of the IL-32 gene. IL-32 alpha induces the macrophage production of inflammatory cytokines, such as interleukin 8 (IL-8), tumor necrosis factor-alpha (TNF-alpha), and macrophage inflammatory protein 2 (MIP-2). IL-32 alpha expression is increased after the activation of T cells, natural killer (NK) cells, and interferon gamma-treated epithelial cells.
Endotoxin: Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
Centrifuge vial before opening, Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws. Upon reconstitution, a small amount of visible precipitate can be expected. A 10% overfill has been added to the total material vialed to compensate for this loss.  Â
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Secreted |
| Tissue Specificity: | Selectively expressed in lymphocytes. Expression is more prominent in immune cells than in non-immune cells. |
| BioGrid: | 114664. 14 interactions. |
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