Human GRO-beta (CXCL2)

Source: Genetically modified E.coli.
Predicted MW: Monomer, 7.9 kDa (73 aa)
Growth regulated protein beta (GRO-beta ), also known as CXCL2, is a chemokine that is secreted by macrophages, neutrophils, and monocytes at sites of inflammation. GRO-beta functions as a chemoattractant for leukocytes and hematopoietic stem cells. GRO-beta activity is mediated through binding the G-protein-coupled chemokine receptor CXCR2.

Endotoxin: Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
Centrifuge vial before opening, Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws. Upon reconstitution, a small amount of visible precipitate can be expected. A 10% overfill has been added to the total material vialed to compensate for this loss.   

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location:	Secreted
Post transnational modification:	The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.
BioGrid:	109177. 6 interactions.

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