Human GPR77 (1-38) Protein, hFc Tag

Product code: 32-17546

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50 µg
$486.00 

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Amount : 50 µg
Purification : The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage condition : Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized proteins are shipped at ambient temperature.
Alternative Name : C5L2; GPF77; GPR77

The protein has a predicted molecular mass of 30.2 kDa after removal of the signal peptide. The apparent molecular mass of GPR77(1-38)-hFc is approximately 35-55 kDa due to glycosylation. This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants.

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