Human CGRPR Protein, mFc Tag
Figure 1. Human CGRPR Protein, mFc Tag on SDS-PAGE under reducing condition.
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| Amount : | 100 µg |
| Purification : | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Content : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. |
| Storage condition : | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Uniprot ID : | Q16602 |
| Alternative Name : | CRLR; CALCRL; LMPHM8 |
Description :Recombinant human CGRPR Protein with C-terminal mouse Fc tag
Background : Enables adrenomedullin binding activity; adrenomedullin receptor activity; and calcitonin gene-related peptide receptor activity. Involved in several processes, including G protein-coupled receptor signaling pathway; cellular response to sucrose stimulus; and receptor internalization. Located in endoplasmic reticulum; endosome; and lysosome. Part of CGRP receptor complex and adrenomedullin receptor complex. Colocalizes with plasma membrane. Implicated in hereditary lymphedema.
Molecular Characterization: mass of 40.0 kDa after removal of the signal peptide. The apparent molecular mass of CGRPR-mFc is approximately 35-70 kDa due to glycosylation.
Tag :C-mouse Fc tag
Background : Enables adrenomedullin binding activity; adrenomedullin receptor activity; and calcitonin gene-related peptide receptor activity. Involved in several processes, including G protein-coupled receptor signaling pathway; cellular response to sucrose stimulus; and receptor internalization. Located in endoplasmic reticulum; endosome; and lysosome. Part of CGRP receptor complex and adrenomedullin receptor complex. Colocalizes with plasma membrane. Implicated in hereditary lymphedema.
Molecular Characterization: mass of 40.0 kDa after removal of the signal peptide. The apparent molecular mass of CGRPR-mFc is approximately 35-70 kDa due to glycosylation.
Tag :C-mouse Fc tag
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