Human ACVR2A(19-42) Protein, mFc Tag
Figure 1. Human ACVR2A(19-42) Protein, mFc Tag on SDS-PAGE under reducing condition.
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| Amount : | 10µg |
| Purification : | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Content : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage condition : | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Gene : | ACVR2A |
| Uniprot ID : | P27037 |
| Alternative Name : | ACVR2; ACTRII,Recombinant human ACVR2A(19-42) Protein with C-terminal mouse Fc tag |
This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jun 2013]
Molecular Weight : The protein has a predicted molecular mass of 29.0 kDa after removal of the signal peptide. The apparent molecular mass of ACVR2A(19-42)-mFc is approximately 25-35 kDa due to glycosylation.
Tag :C-Mouse Fc tag
Molecular Weight : The protein has a predicted molecular mass of 29.0 kDa after removal of the signal peptide. The apparent molecular mass of ACVR2A(19-42)-mFc is approximately 25-35 kDa due to glycosylation.
Tag :C-Mouse Fc tag
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