GAGE12F Recombinant Protein
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Amount : | 10 µg |
Purification : | Greater than 85.0% as determined by SDS-PAGE. |
Content : | GAGE12F protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl and 10% glycerol. |
Storage condition : | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
AA sequence : | MGSSHHHHHH SSGLVPRGSH MGSMSWRGRS TYYWPRPRRY VQPPEMIGPM RPEQFSDEVE PATPEEGEPA TQRQDPAAAQ EGEDEGASAG QGPKPEAHSQ EQGHPQTGCE CEDGPDGQEM DPPNPEEVKT PEEGEKQSQC |
Alternative Name : | G Antigen 12F, GAGE-12F, G Antigen 12F/G/I. |
Source : Escherichia Coli.
GAGE12F Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 140 amino acids (1-117aa) and having a molecular mass of 15.4kDa.GAGE12F is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
GAGE12F
is a member of the GAGE multigene family expressed in a large range of tumors
whereas in normal tissues, his expression is restricted to germ cells. These
genes are organized in clustered repeats, and have a high degree of forecasted sequence
identity, however differ by scattered single nucleotide substitution. Their
sequences contain either the antigenic peptide YYWPRPRRY or YRPRPRRY which is
recognized by cytotoxic T-cells.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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