FOS-B Recombinant Protein(Discontinued)
Shipping Info:
For estimated delivery dates, please contact us at [email protected]
| Amount : | 5 µg |
| Content : | FOS-B in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol. |
| Storage condition : | Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.Please prevent freeze-thaw cycles. |
| Alternative Name : | Protein fosB, G0/G1 switch regulatory protein 3, FOSB, G0S3, AP-1, GOS3, GOSB, MGC42291, DKFZp686C0818, FOS-B. |
Source : Escherichia Coli.
FOS-B Human Recombinant (a.a. 113-151) expressed in E.coli, shows a 32 kDa SDS-PAGE (Including GST).The FOS-B is purified by proprietary chromatographic techniques.
Fos B encodes a nuclear protein of 338 amino acids which has 70% homology with c-Fos, exhibits similar kinetics of expression as c-Fos and forms heterodimers with both c-Jun and Jun B which bind to TRE DNA response elements. Functional homologs of c-Fos and Fos- B include Fra-1 and Fra-2 genes. The 4 members of Fos gene family are: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins which can dimerize with proteins of the JUN family, thus forming the transcription factor complex AP-1. The FOS proteins act as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms exist for Fos B.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
|
There are currently no product reviews
|
.png "ACE2/HEK293 Stable Cell Line")
