FITC Conjugated Anti-CD102 / ICAM-2 Monoclonal Antibody (Clone:CBR-IC2/2)

Figure 1: Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD102 (CBR-IC2/2) FITC antibody (4 μl reagent / 100 μl of peripheral whole blood).

FITC Conjugated Anti-CD102 / ICAM-2 Monoclonal Antibody (Clone:CBR-IC2/2)

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Figure 1: Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD102 (CBR-IC2/2) FITC antibody (4 μl reagent / 100 μl of peripheral whole blood).

Figure 2: Separation of human monocytes (red-filled) from CD102 negative neutrophil granulocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD102 (CBR-IC2/2) FITC antibody (4 μl reagent / 100 μl of peripheral whole blood).

Product code: 30-1069F

Clone name :	CBR-IC2/2
Clonality :	Monoclonal
Application :	FACS
Reactivity :	Human
Conjugate :	FITC

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For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Amount :	100 tests
Isotype :	Mouse IgG2a
Purification :	Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Content :	Formulation: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage condition :	Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.


Gene :	CD102
Gene ID :	3384
Uniprot ID :	P13598
Alternative Name :	ICAM2; CD102
Immunogen Information :	Human CD102 cDNA transfected COS cells

CD102 / ICAM-2 (intracellular cell adhesion molecule-2), a counter receptor of LFA-1 (CD11a/CD18), is a transmembrane glycoprotein with two extracellular IgC-like domains and intracellular C-terminal tail. It is involved in lymphocyte recirculation and homing to the sites of inflammation. Through interaction with integrins it provides to the immune cells costimulatory signals. Expression of CD102 on blood cells (lymphocytes, monocytes, thrombocytes) is lower than on endothelium and follicular dendritic cells. CD102 levels are upregulated in lymph nodes with malignant infiltration.

Specificity: The mouse monoclonal antibody CBR-IC2/2 recognizes an extracellular epitope of CD102 (ICAM-2), an approximately 55 kDa type I transmembrane glycoprotein expressed mainly on vascular endothelial cells and folicular dendritic cells, in lower amount on lymphocytes, monocytes and platelets.

Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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