EGFR(Ab-1070) Antibody

Product code: 35-1427

Clonality : Polyclonal
Application : ICC/IF, IHC, WB
Reactivity : Human

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Available Pack Size(s)

  •   50 µl

  •  100 µl

  • $374.00 

  • $437.00 

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Amount : 100 µl
Purification : Affinity-chromatography
Content : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage condition : Store at 4°C; For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : IGLC1
Gene ID : 1956
Uniprot ID : P00533
Alternative Name : Receptor tyrosine-protein kinase ErbB-1; ERBB1; Proto-oncogene c-ErbB-1
Immunogen Information : Peptide sequence around aa.1068~1072 (R-Y-S-S-D) derived from Human EGFR.

Receptor for EGF, but also for other members of the EGF family, as TGF-a, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentia 

Predicted MW: 175kd
Western blotting: 1:500~1:1000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:200

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Secreted
Post transnational modification: Methylated. Methylation at Arg-1199 by PRMT5 stimulates phosphorylation at Tyr-1197.
Tissue Specificity: Ubiquitously expressed. Isoform 2 is also expressed in ovarian cancers.
BioGrid: 108276. 1217 interactions.
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