Cynomolgus MICA Protein, His Tag

Product code: 32-18472

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  •   50 µg

  •  100 µg

  • $624.00 

  • $799.00 

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Amount : 100 µg
Purification : The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Content : Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.
Storage condition : Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Uniprot ID : WAK97480
Alternative Name : MIC-A; PERB11.1
Description :Recombinant Cynomolgus MICA protein with C-terminal 10×His tag
Background : This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants.
Molecular Characterization: mass of 33.4 kDa after removal of the signal peptide.
Tag :C-10×His tag
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