Abeomics’ proprietary Reporter Cell Lines provide the most advanced system available for screening key pathways involved in immune regulation and inflammation. The innovative Leeporter™ Stable Reporter Cell Lines feature target promoters or upstream response elements for numerous critical pathways such as TLRs/RLRs, Interleukins, p53 pathway, Nrf2, Wnt pathway,STAT and NF-κB pathways, all driving Renilla Luciferase reporter gene expression. These Luciferase Reporter Cell Lines have undergone extensive functional characterization, demonstrating broad working range dynamics and high sensitivity, making them ideal for high-throughput screening of small molecules. Leeporter™ Luciferase Reporter Cell Lines and assay systems are integral to Abeomics Drug Discovery Screening Services and Compound Screening Services and are also available for direct purchase. Abeomics continually expands its offerings with new modulators, compound libraries, and Reporter Cell Lines to explore mechanisms of action and develop potential treatments for various diseases.
Stable Cell Lines are crucial tools for protein production, target validation, and functional assays. Abeomics' portfolio includes stable cell lines for molecules involved in immune modulation pathways, enhancing research and development in therapeutic areas.