CD8B Recombinant Protein

Product code: 32-3453

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20 µg
$388.00 

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Amount : 20 µg
Purification : Greater than 80% as determined by SDS-PAGE.
Content : The CD8B solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.
Storage condition : Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
AA sequence : MGSSHHHHHH SSGLVPRGSH MGSLQQTPAY IKVQTNKMVM LSCEAKISLS NMRIYWLRQR QAPSSDSHHE FLALWDSAKG TIHGEEVEQE KIAVFRDASR FILNLTSVKP EDSGIYFCMI VGSPELTFGK GTQLSVVDFL PTTAQPTKKS TLKKRVCRLP RPETQKGPLC SP
Alternative Name : T Lymphocyte Surface Glycoprotein Beta Chain, CD8 Antigen, Beta Polypeptide 1 (P37), CD8b Molecule, CD8b Antigen, T-Cell Surface Glycoprotein CD8 Beta Chain, CD8B1, LYT3, LY3, LEU2, P37.
Source : Escherichia Coli. CD8B Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 172 amino acids (22-170) and having a molecular mass of 19.2 kDa. CD8B is fused to a 23 amino acid His-tag at N-terminus. CD8B encodes the CD8 beta chain isoforms of the CD8 antigen. CD8 is a cell surface glycoprotein which facilitates efficient cell-cell interactions within the immune system and is located on most cytotoxic T lymphocytes. The T-cell receptor on the T lymphocyte and the co-receptor CD8 antigen identify antigens exposed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional co-receptor is either a heterodimer composed of one alpha and one beta chain or a homodimer composed of two alpha chains. Both alpha and beta chains share substantial homology to immunoglobulin variable light chains.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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