Biotinylated Recombinant Human Polymeric Immunoglobulin Receptor/PIgR (C-His)

Product code: 32-9096

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Available Pack Size(s)

  •   250 µg

  •  25 µg

  • $1,290.00 

  • $464.00 

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Amount : 25 µg
Content : 0.2mg/ml in sterile PBS, pH7.6
AA sequence : Biotinylated Recombinant Human Polymeric Immunoglobulin Receptor is produced by Human 293 Cells. The target gene encoding K19-R639 is expressed with a 8His tag at the C-terminus.
Alternative Name : Polymeric Immunoglobulin Receptor; PIgR; Poly-Ig Receptor; Hepatocellular Carcinoma- Associated Protein TB6; PIGR

Source : Human 293 Cells;
Polymeric Immunoglobulin Receptor (pIgR) is a type I transmembrane glycoprotein. pIgR is expressed by secretory epithelial cells with five Ig-like domains in the extracellular region, and transfer to the basolateral plasma membrane where it can bind larger polymers of IgA (pIgA ) and pentameric IgM. The complex is then transported across the cell to be secreted at the apical surface. During this process, a cleavage occurs and separates the extracellular (known as the secretory component) from the transmembrane segment.

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