Biotinylated Mouse Monoclonal Antibody to Ipilimumab (Clone : 4H6E1D4)
Figure-1 : ELISA binding of Biotin conjugated Lpilimumab Antibody (Clone: 4H6E1D4) with Ipilimumab, Coating antigen: Ipilimumab at 1 µg/ml, Ipilimumab antibody dilution start from 1,000 ng/ml, EC50=3.85 ng/ml.
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| Format : | Purified |
| Amount : | 40 µg |
| Isotype : | Mouse IgG1 |
| Purification : | Protein A chromatography |
| Content : | 0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide. |
| Storage condition : | The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles. |
| Immunogen Information : | Ipilimumab |
Ipilimumab (Yervoy) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Ipilimumab works to activate the immune system by targeting CTLA-4 (Cytotoxic T-lymphocyte protein 4), a negative regulator of cytotoxic T-lymphocyte activity. Ipilimumab binds to CTLA-4, blocking the inhibitory signal, which allows the cytotoxic T-lymphocytes to destroy the cancer cells Anti-Ipilimumab Antibody (4H6E1D4) [biotin], mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Ipilimumab.
ELISA detection: 0.01-0.1 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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