Biotinylated Anti-IL13 antibody(1A1), IgG1 Chimeric mAb
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| Amount : | 10 ?g |
| Isotype : | Rabbit/Human Fc chimeric IgG1 |
| Purification : | Purified from cell culture supernatant by affinity chromatography |
| Content : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % ? 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage condition : | Store at -20?C to -80?C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80?C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Gene : | IL13 |
| Uniprot ID : | P35225 |
| Alternative Name : | IL-13;NC30 |
This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]
ELISA 1/5000-10000
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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