Biotinylated Anti-HER2 antibody(DMC369); IgG1 Chimeric mAb

Product code: 12-9237B

Clone name : DMC369
Clonality : Monoclonal
Application : Flow Cyt
Reactivity : Human

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Available Pack Size(s)

  •   10 µg

  •  100 µg

  • $388.00 

  • $820.00 

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For estimated delivery dates, please contact us at [email protected]


Amount : 100 µg
Isotype : IgG1
Purification : Purified from cell culture supernatant by affinity chromatography
Content : Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Storage condition : Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Gene : Her2
Uniprot ID : P04626
Alternative Name : ERBB2;CD340;HER-2:neu;HER2;MLN19;NEU;NGL;TKR1
This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However; it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer; stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways; such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported; with the most common allele; Ile654:Ile655; shown here. Amplification and:or overexpression of this gene has been reported in numerous cancers; including breast and ovarian tumors. Alternative splicing results in several additional transcript variants; some encoding different isoforms and others that have not been fully characterized.

Flow Cyt 1:100

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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